Endocrine Abstracts

Background: Aggressive prolactinomas are rare neoplasms that are characterized by rapid growth and usually large tumor size, invasion of adjacent structures, an aggressive clinical behavior with little response to conventional treatment, high rate of recurrence, and elevated morbidity and mortality.Case Report: 48-year-old woman diagnosed with life-threatening aggressive prolactinoma was referred to us for evaluation of complementary therapy after therap...

Background: The BRAFV600E mutation is the most common mutation in papillary thyroid carcinoma (PTC). Its presence has been associated with extrathyroid invasion, lymph node metastasis, and tumor recurrence. Recently, assessment of the BRAFV600E mutation status in patients with PTC has been used as a method to predict tumor aggressiveness.Objective: Our aim has been to analyze the prevalence of BRAFV60...

Objective: To assess clinical features, diagnosis, treatment and outcome in patients with pheochromocytoma surgically treated in the past 3 decades in two tertiary referral hospitals.Methods: A retrospective study on clinical and pathological characteristics, treatment, and outcome in patients with pheochromocytoma followed up in specialized neuroendocrinology units who underwent surgery in the period 1981–2016 was performed.R...

Introduction: The widespread use of abdominal computed tomography and magnetic resonance imaging has led to a rise in the diagnosis of incidental adrenal lesions, some of them are pheochromocytomas (Pheo).Objective: To investigate the differences between incidental (IPheo) and symptomatic Pheo (SPheo).Methods: A multicenter retrospective study on clinical and pathological characteristics, treatment and outcome in patients with Pheo...